aka fortune favors the bold

I usually write a blog post at the end of the year, summarizing challenges, experiences, achievements and making projections for the next year. I didn’t follow this tradition in the last turn of the ‘special’ 2020 and instead I decided to write a short story that strengthens the proverb “fortune favors the brave”. …


Coming from a technological background in the Life Sciences domain, it wasn’t clear to me during the first years, which are the boundaries of healthcare and clinical research. I could see overlapping areas between these sectors and it was difficult to understand why they are practically far apart. In this blog post, I am presenting our efforts and strategic decisions to break down the silos of these two sectors, thus making it possible to provide validated personalized medical services.

In my own words, clinical research is a science using clinical trials to research new drugs and interventions (so called “interventional”…


In crisis situations, such as financial recessions, people often refer to the stereotype “crisis creates opportunities”. This is not the case with Covid-19, unless your enterprise is producing sanitizers or masks, or you can develop the vaccine by September. We are all subjects in the biggest medical-, social-, and financial-experiment of all times. This is not even a zero-sum case. We all lose and primarily those that will experience the worst side of the pandemic, i.e. the coronavirus disease.

Nevertheless, there are areas for which this crisis creates obligations that we all need to follow, in order to survive through…


Growth is the Holy Grail for all startups, or at least for most of them. Some others prefer to target higher to the Blitzscaling level of becoming a Unicorn. No matter how you name it, growth phase is the common denominator for all startup trajectories that differentiate them from those that enter the valley of death and those that thrive.

Definitions and metrics vary, depending on the industry and the location. …


I bet that all letters of the alphabet are used in front of aaS to define a new type of service, indicating the domain or the infrastructure. This post is about CRaaS, aka Clinical Research as a Service and describes our efforts to re-define the way clinical research is conducted, using Healthentia platform. I will briefly first describe the specific needs of the clinical research domain, guide you through Healthentia platform and then I will present the challenges of developing and maintaining this platform as a SaaS/PaaS software. It is vital to understand the complex environment of the Life Sciences…


Inspired by a course I was lecturing this week, I came across books that I have read some years ago. Books that will always be valid around entrepreneurship & startups that reminded me the importance of timing and the key parameters that should be considered by all startups. Digging more, I watched a video from Drew Houston, CEO of Dropbox, presenting in front of an audience that was only partially aware about his killing storage service. Drew was presenting milestones from Dropbox, among them the critical question When to launch?, presenting the dipole of Paul Graham (early and often) and…


It is in our nature to compare situations with our experiences from other fields. I see myself doing this often by comparing business with sports, especially when thinking or lecturing about startups.

What it the common denominator for setting up a startup and running it in its first phase? You sprint like there is no tomorrow and you do this on your own in a lonely race without being able to compare your outcome with your competitors. …


I am sure you all know about technology adoption lifecycle, whether because you have read Geoffrey Moore’s book Crossing the Chasm, or empirically, as you are all sitting on this curve for several technologies that you use.

Crossing the chasm in the Technology Adoption Lifecycle

According to Moore each section of the Technology Adoption Lifecycle curve (see above) has its challenges, however the most critical one is at the early adopters, after moving form the innovators. This is the famous “Chasm” that needs to be crossed! …


I am sure you feel like I do, when reading articles or hear news about #AI products and when you meet with #AI experts. I find myself often talking to colleagues, clients and students, entering into discussions about how much #AI are we! Is this normal, or do we live up to the hype with buzzword symptoms? In this story, I am making an approach to define the fair use of #AI and I am looking forward to see your thoughts in the comments.

CBR overview [source: https://ascelibrary.org/doi/full/10.1061/%28ASCE%29CO.1943-7862.0000863]

My first experience with AI started back in 2001. I was coordinating an R&D project, in…


I have to admit that my scientific papers at the end of 90s and beginning of the 2000 had many more mathematical equations, simulations, diagrams, etc. I also recognize a similar pattern in many journal papers I review or cite. For conference proceedings, I don’t need to mention a lot. Apart from a a few credible conferences, most of the papers do not worth much. You all know I am talking about the domains of IT, telecoms and cloud computing. I am not sure if the same applies to all domains.

Does the academic community recognize this? Prof. Ioannidis from…

Sofoklis Kyriazakos

Married, father of 2 sons, Entrepreneur, Innovator, Associate Professor, iSprinter. Blogging about technology, innovation & startups.

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